Alert: Important information about swine flu
Important changes have been announced today to the
way in which the NHS is managing the growing swine flu pandemic in
England. Read the latest advice to help protect yourself, your
family and others.
Last updated: 16.45 BST
The secretary of state for health today announced the
groups that will be given priority for vaccination once a swine flu
vaccine becomes available. The government has placed orders for
enough vaccine for the entire population, but as it will take time
to produce enough vaccine, the most vulnerable groups need to be
given priority.
Andy Burnham said that the vaccine, with the first batches
expected to be available in October, would initially be given to the
following groups, in this order:
- People aged between six months and 65 years in current
seasonal flu vaccine clinical at-risk groups
- All pregnant women (subject to licensing)
- Household contacts of people with compromised immune systems
- People aged 65 and over in the current seasonal flu vaccine
clinical at-risk groups
He said that frontline health and social care workers will also
begin to be vaccinated at the same time as the first at-risk group.
At-risk groups
At-risk groups will be the same as for seasonal flu vaccination,
and include people with serious heart disease, diabetes, and those
with weakened immune systems due to cancer treatment.
The health secretary said: “Although the virus has so far proved
to be mild in most people, for others it has been more serious.
By vaccinating high-risk groups first, we aim to protect those most
vulnerable to this virus.”
The list has been drawn up according to advice from the Joint
Committee on Vaccination and Immunisation. The group of independent
experts reviewed the evidence and advised the Department of Health
on the crucial risk groups to be offered vaccination to reduce the
rate or possibility of serious illness.
A vaccination programme for the rest of the population will be
based on the evolution of the pandemic as well as new clinical data
on the use of the vaccine.
People in the priority groups outlined above do not need to take
any action yet. Further announcements will be made when the
vaccination strategy is ready, and those who need a vaccine will be
contacted.
Weekly pandemic flu update
Other key points made at this week’s briefing by the chief
medical officer (CMO) included:
- There has been a further reduction in the rates of flu-like
illness and related activity this week. There were an estimated
25,000 new cases last week compared to 110,000 new cases two
weeks before.
- Weekly GP consultation rates decreased over the last week in
England.
- There are 371 patients in hospital with swine flu, 39 of
whom are in critical care.
- There have been 44 confirmed deaths in England, bringing the
UK total to 49.
- There is still no sign of the virus mutating into a more
dangerous form, or developing resistance to drugs.
Vaccine progress
The World Health Organization (WHO) confirmed last week that the
first swine flu vaccines are likely to be licensed for use in the
general population in September. Initial batches of an H1N1 vaccine
have already been produced, and clinical trials are underway.
"The quality controls on today's vaccine are much better than
they were 30 years ago," said the WHO, which also oversees the
safety checks on the seasonal flu jab.
National Pandemic Flu Service
The National
Pandemic Flu Service was launched in July. This new online
service assesses patients for swine flu and, if required, gives
them an authorisation number that can be used to collect antiviral
medication.
The system, which can also be accessed by telephone, will take
the strain off GPs as swine flu spreads. For the moment, it is only
being used in England.
“The National Pandemic Flu Service is a new self-care service
which will give people with pandemic swine flu symptoms fast access
to information and antivirals,” said a Department of Health
spokesman.
“This new service will free up GPs, enabling them to deal with
other illnesses that need their urgent attention.”
The launch of the new system means important changes to the
official advice that is given to people who think they may have
swine flu. That advice – and the new system itself – is supported by
the Royal College of General Practitioners.
Latest advice
If you have flu-like symptoms and are concerned that you may have
swine flu, the advice is to stay at home and check your symptoms at
the National
Pandemic Flu Service.
Call your GP if:
- you have a serious underlying (existing) illness,
- you're pregnant,
- you have a sick child under one year old,
- your condition suddenly gets much worse, or
- your condition is still getting worse after seven days (five
for a child).
For people who do not have internet access, the National Pandemic
Flu Service can be accessed by phone on:
Telephone: 0800 1 513 100
Minicom: 0800 1 513 200
For more information on the National Pandemic Flu Service, go to
Flu Service: questions and answers.
People in Scotland, Wales and Northern Ireland can visit
www.direct.gov.uk/pandemicflu
Swine flu latest from the NHS
The government today launched the
National Pandemic
Flu Service, a new online service that will assess patients for
swine flu and, if required, provide an authorisation number that can
be used to collect antiviral medication.
If you have flu-like symptoms find out what should you do
-
If you have
flu-like symptoms and are concerned that you may have swine
flu:
- you have a serious underlying illness
- you are pregnant
- you have a sick child under one year old
- your condition suddenly gets much worse
- your condition is still getting worse after
seven days (or five days for a child)
Note: The National Pandemic Flu Service is a
self-care service that will asses your symptoms and, if
required, provide an authorisation number which can be used to
collect antiviral medication from a local collection point. For
those who do not have internet access, the same service can be
accessed by telephone on:
- Telephone: 0800 1 513 100
- Minicom: 0800 1 513 200
For more information on the National Pandemic Flu Service go
to
Flu Service – Q&A
Key actions
Swine flu is spreading fast in
the UK. Prepare now by:
- Learning to recognise the symptoms of swine flu
- Establishing ‘flu friends’ - friends and relatives who
can help if you fall ill
- Keeping paracetamol-based cold remedies in the house
- Having a thermometer available so you can check your
temperature if needed
Note: If you have elderly or vulnerable
neighbours please check on them. They may need your help but be
reluctant to ask for it. It is important you do what you can.
Note:
To order a Braille copy of the swine flu information leaflet,
call the swine flu information line on 0800 1 513 513
Good hygiene
Preventing the spread of germs
is the single most effective way to slow the spread of diseases
such as swine flu. You should always:
- Ensure everyone washes their hands regularly with soap
and water
- Clean surfaces regularly to get rid of germs
- Use tissues to cover your mouth and nose when you cough
or sneeze
- Place used tissues in a bin as soon as possible
What is swine flu (influenza A H1N1)?
Although symptoms of swine flu have generally been mild, a
small number of patients will develop more serious illness.
Certain groups of people, and people with other health
conditions, such as heart or lung disease, are at increased
risk.
Find out more about the cause of swine flu and how it differs
from ordinary flu.
Scotland, Wales and Northern Ireland
If you live in Scotland, Wales or Northern
Ireland go to this
pandemic flu
information page. It will direct you to swine flu
information and treatment advice in your area.
-
Swine flu is the common name that has been given to a new
strain of influenza. It is called swine flu because it is
thought to have originated in pigs, but this is not known for
certain.
The most common symptoms are fever, sore throat, diarrhoea,
headache, feeling generally unwell and a dry cough – in other
words, symptoms very similar to seasonal influenza. Most people
recover within a week, even without special treatment.
Pandemic
The virus was first identified in Mexico in April and has
since become a pandemic, which means it has spread around the
globe. It has spread quickly because it is a new type of
influenza virus that few, if any, people have full resistance
to.
Flu pandemics are a natural event that occur from time to
time. Last century, there were flu pandemics in 1918, 1957 and
1968, when millions of people died across the world.
So far the new virus is known to have infected more than
119,000 people worldwide. However, this figure is almost
certainly a large underestimate because it reflects only those
cases which have been confirmed by laboratory tests.
In the majority of cases the virus has proved relatively
mild. However, more than 700 people have died globally and its
'risk profile' is still not fully understood. For this reason,
and because all viruses can mutate to become more potent,
scientists are advising caution.
The situation in the UK
There have been an estimated 55,000 cases in the UK since the
outbreak started here on 27 April. Of these, over 600 have
involved hospitalisation, and 31 people have died.
The UK formally moved from a 'containment' to a 'treatment'
phase for swine flu on 2 July. This meant that intensive efforts
to contain swine flu, via automatic school closures, for
example, ended in order to free up capacity to treat the
increasing numbers of people who are contracting swine flu
daily.
As in other countries, the majority of cases reported so far
in the UK have been mild. Only a small number have led to
serious illness, and these have frequently been where patients
have had underlying health problems.
There has been an argument put forward that government should
restrict antivirals to those groups who are most at risk of
developing serious complications from swine flu. In other words,
if people are otherwise healthy, then the NHS should let the
virus run its course, treating it with paracetamol and bed rest
as you would normal flu.
However, the government's Scientific Advisory Group on
Emergencies (SAGE) believes that there is still some doubt about
the risk profile of the virus. For instance, there are reports
of some cases in Argentina where young, healthy adults have
apparently become extremely ill from swine flu.
While there is still this doubt, the government has decided
to offer the antiviral medicines Tamiflu or Relenza to everyone
confirmed with swine flu.
High-risk groups
Some people are more at risk of serious illness if they catch
swine flu, and will need to start taking antivirals as soon as
they are confirmed with the illness. On occasion, doctors may
advise some high-risk patients to take antivirals before they
have symptoms if someone close to them has swine flu.
The risk profile of the virus is still being studied but it
is already known that the following people are particularly
vulnerable:
- people with:
- chronic lung disease,
- chronic heart disease,
- chronic kidney disease,
- chronic liver disease,
- chronic neurological disease (neurological disorders
include motor neurone disease, multiple sclerosis and
Parkinson's disease),
- immunosuppression (whether caused
by disease or treatment), and
- diabetes mellitus,
- patients who have had drug treatment for asthma in the
past three years,
- pregnant women,
- people aged 65 years and older, and
- children under five years old.
Swine flu vaccine
A vaccine to protect against swine flu is being developed but
it is not available yet.
The first batches of vaccine are expected to arrive in the
autumn, and 30 million double doses – enough for half the
population – are expected to be available by the end of the
year.
The government has ordered enough vaccine for the whole
population and, when it becomes available, will focus on those
at the greatest risk first.
Catch it, bin it, kill it
Although the UK has moved to a treatment phase for swine flu,
it is important that people continue to do everything they can
to stop the virus from spreading.
The key is to practise good respiratory and hand hygiene. In
other words, remember to Catch it, Bin It, Kill It. Catch your
sneeze in a tissue, place it quickly in a bin and wash your
hands and surfaces regularly to kill the virus.
-
Advice
for pregnant women
If you are pregnant, you are in one of the high-risk
groups for swine flu, so it is important you read this page
carefully and follow the advice to protect yourself and your baby.
This page explains why pregnant women are at greater risk from
swine flu, what those risks are, the special precautions you should
take and the safety information for swine flu treatments.
Why pregnant women are more at risk
In pregnancy, the immune system is naturally suppressed. This
means that pregnant women are more likely to catch swine flu, and if
they do catch it, they are more likely to develop complications (see
below).
However, it is important not to panic: your immune system still
functions and the risk of complications is still very small. The
majority of pregnant women will only suffer mild symptoms.
Symptoms and risks
If you are pregnant and you catch swine flu, the symptoms are
expected to be similar to those of regular human seasonal flu.
Typical symptoms are fever and a cough, and sometimes also
tiredness, headache, aching muscles, runny nose, sore throat, nausea
or diarrhoea.
Most pregnant women will have only mild symptoms and recover
within a week. However, there is evidence from previous flu
pandemics that pregnant women are more likely to develop
complications from flu.
Possible complications are pneumonia (an infection of the lungs),
difficulty breathing and dehydration. In pregnant women, these are
more likely to happen in the second and third trimester.
If a pregnant woman develops a complication of swine flu, such as
pneumonia, there is a small chance this will lead to premature
labour or miscarriage. There is not yet enough information to know
precisely how likely these birth risks are.
It is therefore important to be well prepared and to take
precautions against swine flu.
Special precautions
If you are pregnant, you can reduce your risk of infection by
avoiding unnecessary travel and avoiding crowds where possible.
Pregnant women should also follow the general advice outlined in
the box, top right. Good hygiene is essential.
If a family member or other close contact has swine flu, your
doctor may prescribe you antiviral medication (usually Relenza) as a
preventative (prophylactic) measure.
If you think that you may have swine flu, call your doctor for an
assessment immediately. If your doctor confirms swine flu over the
phone, you will be prescribed antiviral medication to take as soon
as possible (see box, left).
Unless you have swine flu symptoms, carry on attending your
antenatal appointments so you can monitor the progress of your
pregnancy.
Swine flu treatment
Antivirals
If you are pregnant and diagnosed with swine flu, you will
usually be given a course of the antiviral drug Relenza, which is
inhaled using a disk-shaped inhaler. It is recommended for pregnant
women because it easily reaches the throat and lungs, where it is
needed, and does not reach significant levels in the blood or
placenta. Relenza should not affect your pregnancy or your growing
baby.
However, if your doctor or midwifery specialist thinks that a
different medicine is needed (for instance, if you have unusually
severe flu), you will be given Tamiflu instead.
An expert group reviewed the risk of antiviral treatment in
pregnancy, which is extremely small - much smaller than the risk
posed by the symptoms of swine flu.
Some people have had wheezing or serious breathing problems when
they have used Relenza. Relenza is therefore not recommended for
people with asthma or COPD. Other possible side
effects include headaches, diarrhoea, nausea and vomiting.
Nausea is a known side effect of Tamiflu, in a small number of
cases.
If you take an antiviral and have side effects, see your
healthcare professional to check that you are ok. Then report your
suspected drug reaction to the Medicines and Healthcare products
Regulatory Agency (MHRA) via their new new
online system.
Painkillers
You can also take paracetamol-base cold remedies to reduce fever
and other symptoms. Paracetamol is safe to take in pregnancy.
However, pregnant women should not take non-steroidal
anti-inflammatory drugs (NSAIDs) such as ibuprofen (Nurofen).
Vaccine
It will be in the autumn before a swine flu vaccine becomes
available. When it is available, there will be guidelines on which
groups of people are a greater priority for vaccination.
You should take up the swine flu vaccine as soon as it is offered
- it will not harm you or your unborn baby.
If you think you have swine flu
Check your symptoms
Follow the link below or call 0800 1 513 100
(textphone - 0800 1 513 200)
If you are in England and think you may have swine flu, check
your symptoms online by visiting the new National Pandemic Flu
Service website, or by calling 0800 1 513 100 (0800 1 513 200
for Textphone).
If you do have swine flu, you will be given a unique access
number and told where your nearest antiviral collection point
is.
Your 'flu friend' – a friend or relative who does not have
swine flu – can use this number to pick up your antivirals for
you. Your flu friend must show their own ID as well as yours.
Acceptable forms of ID include:
- a utility bill
- passport
- a credit or debit card
- driving licence
- NHS card
Contact your doctor
You should contact your doctor direct rather than using the
National Pandemic Flu Service if:
- you have a serious underlying illness
- you are pregnant
- you have a sick child under one year old
- your condition suddenly gets much worse
- your condition is still getting worse after seven days
(five for a child)
Scotland, Wales and Northern Ireland
If you are in Scotland, England or Northern Ireland the
advice is different.
Follow the 'information around the UK' link below.
Vaccine and medication
Swine flu is being treated with anti-viral drugs. A swine flu
vaccine is expected to be available by August.
Vaccine
As swine flu is a new virus, a new vaccine had to be
developed to deal with it.
The first batch of the vaccine is expected to be available by
August, with 60 million doses of the swine flu vaccine expected
to be available by the end of the year.
The government has ordered enough vaccine for the whole
population, but to reduce the impact of swine flu those at
greatest risk will be given priority.
Anti-viral drugs
Anti-viral drugs work by preventing the flu virus from
reproducing - to be effective you need to take them within 48
hours of the onset of symptoms. This means the illness may be
shortened by a day and reduce the risk of complications.
Read the section above, ‘if you have the flu’ before
contacting your doctor about anti-viral drugs.
Prevention
Flu video
There's a simple way to remember this:
CATCH IT. BIN IT. KILL IT.
To reduce the risk of catching or spreading the virus you
should:
- cover your mouth and nose when coughing and sneezing,
using a tissue
- throw the tissue away quickly and carefully
- wash your hands regularly with soap and water
- clean hard surfaces (like door handles and remote
controls) frequently with a normal cleaning product
Preparation
Go to NHS Choices for health advice on swine flu,
including the latest advice on symptoms, prevention,
treatment and causes
A global pandemic has been declared. To prepare:
- always carry tissues - catching the germs in a tissue
could help limit the spread of the virus
- know your NHS number (this will be in NHS letters or
prescriptions)
- keep up to date with the latest help and advice
available through radio, TV and the internet – follow the
links below for more advice on Directgov
- confirm your ‘flu friends’ - these are friends and
neighbours who can help you if you become ill; they could
get your medication or food for you so that you don’t have
to leave the house - this will help stop the virus from
spreading
- have a two-week stock of food and other supplies in case
you and your family are ill
Face masks
Although face masks have been given out in Mexico, there is
no actual evidence that proves wearing a face mask will stop you
getting the virus. It’s more effective to use tissues when
sneezing and coughing and wash your hands regularly.
Swine flu vaccine being tested
Behind the Headlines
Brought to you by the NHS Knowledge Service
Fertilised eggs are injected with samples of
influenza viruses
Clinical trials of newly developed vaccines for swine
flu have begun in the USA and Australia. These human
studies will gather data on the safety and effectiveness
of the vaccine.
Key points
The National Institute of Allergy and Infectious
Diseases (NIAID), which is part of the National
Institutes of Health in the USA, announced yesterday
that a network of medical research institutions is about
to begin a series of clinical trials to gather safety
and efficacy data about some of the new influenza
vaccines.
- At the same time, two vaccine manufacturers in
Australia (CSL and Vaxine) have also begun testing
their vaccine in healthy adult volunteers.
- The clinical trials will provide important early
safety and efficacy data about the vaccines. In
particular, the researchers will be monitoring
adverse effects and immunogenicity (how well the
vaccine provokes an immune response). They will also
be assessing the dose required to be effective and
whether the vaccine can be given alongside seasonal
influenza vaccination.
- The American trials will be in healthy adult
volunteers and in elderly volunteers who are also
receiving the seasonal vaccine. If early results are
positive, further studies may begin in healthy
adolescents and children.
- The trials may take some months to complete, and
the vaccination programmes are likely to begin
before the full results are available. However,
there should be sufficient results by September or
October to spot real safety concerns and to allow
governments to begin planning for the use and
distribution of the new vaccines. Safety will
continue to be monitored through surveillance when
vaccination programmes are introduced nationally.
What are the WHO’s current recommendations for
vaccines?
At a special meeting of the Strategic Advisory Group
of Experts (SAGE) on July 07 2009, the WHO considered
the potential options for vaccine use. They came up with
some recommendations that were endorsed by the WHO
Director-General, including:
- Healthcare workers should be immunised first.
- For other groups it is suggested that countries
should decide their own vaccination policies and
priority orders depending on country-specific
conditions, possibly commencing with pregnant women
and anyone aged over six months with one of several
chronic medical conditions, followed by healthy
young adults between 15 and 49 years of age, healthy
children, healthy adults aged 50 to 64 years and
healthy adults aged 65 years and above.
- Post-marketing surveillance of the vaccine is
very important, particularly in certain population
groups. This is because some new technologies are
involved in the production of these vaccines and
these have not yet been fully tested in certain
groups. It is also important that results of this
surveillance are shared widely in the international
community so that countries can make any necessary
adjustments to their vaccination policies.
- The production of particular types of vaccine
formulations was also promoted, including live
attenuated viruses and those that have oil-in-water
adjuvants, which would help to protect against
drifted strains of the virus (slightly mutated
versions of the virus).
How are vaccines made?
To make a vaccine, a large amount of the virus or
bacteria is needed. In the case of swine flu, the US
Centers for Disease Control and Prevention (CDC) began
isolating and preparing strains of the swine flu virus
as soon as the first human case became known. These
strains were sent to its counterparts in other countries
including the National Institute for Biological
Standards and Control (NIBSC) in the UK. These
organisations prepare the virus strains to be used in
making the vaccine.
Viruses can be grown in hens’ eggs, but often the
infectious influenza virus strains do not grow well in
eggs. To get around this, the infectious virus is
injected into the eggs with another influenza virus that
thrives in eggs. The two viruses swap pieces of their
genetic material and produce hybrids, some of which both
grow well in hens’ eggs and also have the elements of
the disease-causing virus needed for a vaccine. These
hybrids are isolated and the best candidate for making a
vaccine is selected. This chosen hybrid strain is then
grown and distributed to vaccine manufacturers.
The vaccine manufacturers use dead or weakened virus
to create the vaccine. Other constituents can also be
added to the vaccine, such as a suspending fluid to
carry the virus into the body, preservatives and
stabilisers that allow the vaccine to be stored safely,
and chemicals to help the vaccine to promote an immune
response.
When will a vaccine be available?
Vaccine development usually takes about six months
and it began in April 2009. The WHO suggests that the
first doses of influenza A H1N1 vaccine are expected as
early as September 2009. The UK government says that the
first batches of vaccine are expected to arrive in the
autumn, and 30m double doses (enough for half the
population) are expected to be available by the end of
the year. The government has ordered enough vaccine for
the whole population, and when it becomes available will
focus on those at the greatest risk first.
Who will be a priority for vaccination?
The administration of the vaccines will need to be
prioritised. The decision on prioritisation of the
population will be taken on the basis of which groups
are being most affected by the virus, when the vaccine
arrives and how best to protect the NHS from being
over-stretched.
How effective and safe will the vaccine be?
Vaccination is very effective in preventing and
reducing the impact of serious illness. Although
vaccines are not 100% effective and can become less
effective if the virus mutates, they still offer some
protection. Current flu vaccines last for about a year
and give about 70-80% protection against infection with
strains of influenza virus that are very similar to
those used to make the vaccine. It is too early to
predict how the swine flu virus might mutate. The WHO is
closely monitoring it for changes, and this will help
countries to make a quick response if the virus
undergoes important changes.
The human trials that are currently underway will
provide some evidence of the short-term safety and
effectiveness of the vaccines. In particular, the
researchers will be monitoring side effects and also how
effectively the vaccine prompts a response from the
immune system (its immunogenicity). The vaccines will be
approved for use by national authorities. In this
country the Medicines and Healthcare products Regulatory
Agency (MHRA) is responsible for monitoring the safety
of flu medicines and vaccines. Safety monitoring will be
ongoing once the vaccine programme is introduced.